diff --git a/lisp/org-latex-preview.el b/lisp/org-latex-preview.el
index 629d11bac..d554d4820 100644
--- a/lisp/org-latex-preview.el
+++ b/lisp/org-latex-preview.el
@@ -1492,12 +1492,24 @@ The path of the created LaTeX file is returned."
           "\n\\usepackage[active,tightpage,auctex]{preview}\n"))
         (write-region-inhibit-fsync t)
         (coding-system-for-write buffer-file-coding-system))
+    (when org-latex-preview-use-precompilation
+      (if-let ((format-file (org-latex-preview-precompile processing-info header)))
+          ;; Replace header with .fmt file path.
+          (setq header (concat "%& " (file-name-sans-extension format-file)))
+        (display-warning
+         '(org latex-preview disable-local-precompile)
+         (concat "Precompile failed, disabling LaTeX preview precompile in this buffer."
+                 "\n  To renable, run `(setq-local org-latex-preview-use-precompilation t)' or reopen this buffer."
+                 (pcase (plist-get processing-info :latex-processor)
+                   ("lualatex"
+                    "\n  LuaLaTeX is known to be problematic, if you might be able to help please get in touch with emacs-orgmode@gnu.org.")
+                   ("xelatex"
+                    ;; Note: <https://tex.stackexchange.com/questions/395965/precompile-with-xelatex-and-fontspec> might be helpful.
+                    "\n  The current XeTeX approach does not support fontspec, if you might be able to help please get in touch with emacs-orgmode@gnu.org."))
+                 "\n "))
+        (setq-local org-latex-preview-use-precompilation nil)))
     (with-temp-file tex-temp-name
-      (insert (if-let ((format-file
-                        (and org-latex-preview-use-precompilation
-                             (org-latex-preview-precompile processing-info header))))
-                  (concat "%& " (file-name-sans-extension format-file))
-                header))
+      (insert header)
       ;; The \abovedisplayskip length must be set after \begin{document} because
       ;; it is usually set during the font size intialisation that occurs at
       ;; \begin{document}.  We can either modify the \normalsize command to set